Posted: 8/12/2009 - 2 comment(s) [ Comment ]
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Category: Hepatitis B

Today I presented on the Jade Ribbon Campaign as a model program for engaging the API population in HBV outreach, education and screening events at the CDC National Conference on Health Communication, Marketing and Media.  (Whew, that was a mouthful!)  I have to say that I was actually a little nervous (and Amy pointed out to me afterwards that I did get a red during my presentation…) but I quickly got over any anxiety when I started speaking about the Jade Ribbon Campaign and expressed my genuine passion for eliminating the silent killer and health disparity, hepatitis B.  The Asian Liver Center has given me many opportunities to grow both personally and professionally.  This presentation to the CDC was another example of an exciting chance to showcase our center’s work and even highlight some of the projects that I have been working on over the past year.  I will be uploading my presentation to the Asian Liver Center’s website when I return from Atlanta so please feel free to check it out!

The CDC Health Marketing Conference has brought together some interesting and insightful speakers, as well as a gung-ho group of twittering tweeters who are all using the conference hashtag #nchcmm09.  This has really been my initial experience to see firsthand how twitter, hashtags and tweets work in the professional setting.  Everyone at the conference has been actively updating their status with interesting facts from speakers and information about their own organizations.  In fact, a tweetup has been scheduled for this evening!  We’ll just see how adventurous I get.  I feel like I may have to study my key twitter vocab words before I go so I don’t make a fool out of myself (and embarrass Amy).  If you want to help me figure out twitter and follow my daily activities at the Asian Liver Center, please follow me @AlenaGroopman.  And who knows, maybe one day when I master this whole twitter thing, my twitter updates will automatically update my eastvillagers status or viceversa...

Posted: 8/11/2009 - 1 comment(s) [ Comment ]
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Category: Hepatitis B

Article from JHSPH News (August 10, 2009): http://www.jhsph.edu/publichealthnews/articles/2009/nelson_hbv.html

Women with Hepatitis B Virus (HBV) infection who experience multiple pregnancies have a reduced risk of developing hepatocellular carcinoma, according to a study led by researchers at the Johns Hopkins Bloomberg School of Public Health. Researchers evaluated the incidence and risk factors for hepatocellular carcinoma among pregnant women in Taiwan who were screened for HBV infection to prevent transmission of the virus to their infants.  They found that markers of active HBC viral replication were associated with a greater risk of later developing hepatocellular carcinoma than those who had inactive chronic HBV infection. The results are published in the July 15, 2009, issue of the Journal of the National Cancer Institute.


“Previous studies have primarily focused on the relationship between HBV and hepatocellular carcinoma in men, since the rate of hepatocellular carcinoma among men infected with HBV is 2 to 6 times higher than among HBV-infected women. This is the largest published study that examines the association of HBV infection with liver cancer among women,” said Kenrad Nelson, MD, author of the study and professor with the Bloomberg School’s Department of Epidemiology. “Although chronic HBV- infected women are at increased risk of developing hepatocellular carcinoma, we found that the more pregnancies an HBV-infected woman experienced, the lower her risk of developing liver cancer within the next 12 years. Thus leading us to question of whether estrogen and progesterone secretion during pregnancy may have provided some protection from HBV-induced liver cancer. These data help explain why the rates of hepatocellular carcinoma have been significantly higher among men than women in every population that has been studied.”


Nelson, along with colleagues from the Bloomberg School of Public Health, Academia Sinica, the National Taiwan University and the Centers for Disease Control of Taiwan, used data from four population based registries and examined information about pregnant women who were tested for hepatitis B surface antigen and e antigen between 1983 and 2000 and subsequent diagnoses of hepatocellular carcinoma. Researchers found that risk for hepatocellular carcinoma during follow-up was statistically significantly higher among pregnant women with chronic, active or persistent HBC infections or who underwent hepatitis B surface antigen seroclearance, than among HBV-unexposed women. Risk decreased as parity increased, independent of hepatitis B surface antigen status and age. 


Hepatocellular carcinoma is the most common form of liver cancer in adults that stems from the major cell type of the liver, hepatocytes. Hepatocellular carcinoma is not as common in the U.S. as it is in Asia, however it has increased significantly in the U.S. during the past two decades. The recent increased incidence is thought to be related to an increased number of persons with chronic infections with hepatitis C and B viruses. Worldwide, liver cancer is a leading cause of cancer death, especially among men, and is especially prevalent in parts of Asia and Africa where chronic HBV infections that have been acquired at birth or in early childhood are common.


“Although women who were persistently hepatitis B surface antigen-positive had an approximately threefold increase in hepatocellular carcinoma risk compared with those who cleared hepatitis B surface antigen, the loss of hepatitis B surface antigen was still associated with an approximately eightfold increased risk for hepatocellular carcinoma compared with those with no evidence for chronic HBV infection. This suggests that the initiation of cacinogenesis by HBV may proceed independent of the degree of activity of the HBV infection in many persons with chronic HBV infection,” said lead author and Bloomberg School graduate Chyng-Wen Fwu, PhD.


“Hepatitis B Virus Infection and Hepatocellular Carcinoma Among Parous Taiwanese Women: Nationwide Cohort Study” was written by Chyng-Wen Fwu, Yin-Chu Chien, Gregory D. Kirk, Kenrad E. Nelson, San-Lin You, Hsu-Sung Kuo, Manning Feinleib and Chien-Jen Chen.


The research was supported in part by the Department of Health, Executive Yuan, Taiwan.


Media contact for Johns Hopkins Bloomberg School of Public Health: Natalie Wood-Wright at 410-614-6029 or nwoodwri@jhsph.edu.
 

Posted: 8/11/2009 - 3 comment(s) [ Comment ]
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Category: Hepatitis B

It’s been a busy summer at the Asian Liver Center!  I can’t believe that when I make it back to the Bay Area after this brief work trip to the East Coast that some of our wonderful summer interns will already be heading back to school (or taking a well-deserved vacation!)

YLC was incredible!  I am completely amazed by all of the creativity and passion of the high school participants, the enthusiasm and energy of the Jade Ribbon Youth Council, and the dedication and fun-loving spirits of the ALC Summer Interns.  Together with the great leadership of our Outreach Coordinator, Ms. Amy Yu, we have completed our Seventh Annual Youth Leadership Conference on Asian and Pacific Islander Health.  And can you believe that we’re already starting to plan for even more exciting speakers and team challenges next year?  We’ll keep you all updated…

I am currently in Atlanta, Georgia with @missamyyu for the CDC National Conference on Health Communication, Marketing and Media…and whew, it is HOT!  Thank goodness for air conditioning, something you really don’t find yourself ever needing when the fog rolls in over San Francisco.  I am just getting myself ready to present on the Jade Ribbon Campaign tomorrow morning so wish me luck!  Want to follow the conference’s events and updates on twitter?  #nchcmm09

Have a wonderful day!

Alena

And yes, for all my zumba peps out there, I will be teaching on Thursday night so be there!